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NCT00260559Recruiting

Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life

University of Pittsburgh

Start Date

5/1/1999

Completion Date

12/1/2050

Summary

To assess short and long term outcomes after minimally invasive esophagectomy compared to open esophagectomy. To compare both standard outcome measures as well as patient derived outcome measures, in particular, quality of life (QOL). To look at the applicability of this QOL instrument to this patient group.

Detailed Description

Assess short and long term outcomes after minimally invasive esophagectomy(MIE) compared to open esophagectomy. Measure standard observer derived outcomes such as morbidity, mortality, tumor recurrence and also patient derived outcomes, in particular quality of life (QOL) using the MOS SF36 questionnaire. Evaluate whether the SF36 will accurately reflect pre and postoperative changes in clinical status in this patient group.Compare the results of this global QOL instrument (SF 36) to disease specific scales of dysphagia and reflux. Assess the impact of adjuvant or neoadjuvant therapy on QOL in this patient group and determine if any advantages of MIE can be demonstrated.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Patients scheduled for MIE (Minimally Invasive Esophagectomy) * Patients scheduled for open esophagectomy * Signed informed consent Exclusion Criteria: * Patients who are unable to comprehend or complete the QOL instruments. * Patients less than 18 years of age.

Interventions

PROCEDURE

Questionnaires

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Conditions

EsophagectomyEsophageal Cancer

Locations

University of Pittsburgh Medical Center - Department of Cardiothoracic Surgery

Pittsburgh, Pennsylvania 15213

United States

UPMC - Hillman Cancer Center

Pittsburgh, Pennsylvania 15232

United States