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NCT00537004Recruiting

Language in Primary Progressive Aphasia

Northwestern University

Start Date

5/1/2007

Completion Date

4/1/2027

Summary

The purpose of this study is to further define the neurological and linguistic deterioration in primary progressive aphasia.

Detailed Description

The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral, anatomical and physiological changes in people with PPA throughout the course of the illness. The researchers in this study want to increase awareness of PPA, educate others about this unique disorder, and to encourage more research to eventually develop therapies. During the three-day research program, participants will be asked to undergo neuropsychological testing (paper and pencil tests that evaluate cognition), advanced imaging (MRI and PET), cognitive experiments, and other computer and language testing batteries. Participants may be asked to return every two years to complete the same measures. For participants not living near Chicago, IL, flights and accommodations (for both the person with PPA and their companion) will be covered by the study.

Eligibility Criteria

Age Range: No minimum to No maximum

Inclusion Criteria: * Diagnosis of primary progressive aphasia * Right-handed * Native English speaker * Visual acuity of 20/30 corrected * Adequate hearing to follow conversation * Safe for an MRI scan Exclusion Criteria: * Left-handedness * Claustrophobia * Presence of significant medical illness that initially or in the future could interfere with continued participation in the study

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Conditions

Primary Progressive Aphasia

Locations

Northwestern University

Chicago, Illinois 60611

United States