NCT02025023PHASE3Recruiting

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

University of Washington

Start Date

12/1/2013

Completion Date

7/1/2026

Summary

Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.

Detailed Description

This is a prospective randomized interventional study comparing four current standard-of-care treatments for chalazia: incision and curettage, local injection of triamcinolone, local injection of 5-FU, and local injection of combination triamcinolone/5-FU.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Single or multiple chalazia in a single eyelid Exclusion Criteria: * Chalazia present for less than one month and no previous injection or incision and curettage

Interventions

DRUG

5-fluorouracil Injection

DRUG

Triamcinolone Acetonide

PROCEDURE

Incision and Curettage

DRUG

Triamcinolone Acetonide/5-fluorouracil mixture

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Conditions

Chalazion

Locations

University of Washington Eye Institute at Harborview

Seattle, Washington 98104

United States