NCT02253030RecruitingAccepts Healthy Volunteers
OCT Angiography in Wet AMD
Oregon Health and Science University
Start Date
9/1/2014
Completion Date
12/1/2026
Summary
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD) 2. evaluate patients undergoing treatment for wet AMD 3. determine if reduced flow to the choroid is a risk factor for developing wet AMD.
Eligibility Criteria
Age Range: 50 years to 100 years
Inclusion Criteria (Groups with wet AMD):
* Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered
Inclusion Criteria (Group with healthy eyes)
* No evidence of retinal disease
* Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx)
* No recent eye surgery in the last 4 months
* No significant cataract to interfere with the quality of the imaging
Exclusion Criteria (All Groups):
* Inability to give informed consent
* Significant kidney disease
* Blood pressure greater than 180/110
* Previous macular laser treatment
* Inability to maintain stable fixation during OCT imaging
* Visual acuity worse than 20/200
Interventions
DEVICE
Optical Coherence Tomography
Conditions
Neovascular (Wet) Age-related Macular Degeneration (AMD)
Locations
Casey Eye Institute, Oregon Health & Science University
Portland, Oregon 97239
United States