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NCT02302742RecruitingAccepts Healthy Volunteers

Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

University of Kansas Medical Center

Start Date

3/22/2011

Completion Date

12/1/2026

Summary

PROGECT is a registry for patients with Triple Negative breast cancer (TNBC) or patients who have an identified germline mutations (such as a mutation on the BRCA1 or BRCA2 genes).

Detailed Description

This study is being done to collect cancer-related information from patients with triple negative breast cancer and patients with hereditary genetic mutations. This information will help us better understand the link between genetic changes and cancer outcome in patients with triple negative breast cancer.

Eligibility Criteria

Age Range: No minimum to No maximum

Inclusion criteria include: Triple Negative Breast Cancer * ER/PR \<10% and HER negative per current ASCO/CAP guidelines * Stages I-IV * Any age at diagnosis * Patient must be within 5 years of diagnosis * Eligible regardless of genetic testing status * Genetic testing recommended for patients meeting NCCN and Medicare guidelines AND/OR Germline mutation Carriers * Patients with deleterious or uncertain mutations in HBOC genes (BRCA, PTEN, P53, -PALB2 etc) are eligible regardless of type/site of cancer * Healthy patients harboring mutations also eligible * There is no time limit from the time of diagnosis of cancer and enrollment. * Eligible regardless of personal history of cancer Exclusion Criteria include: Triple Negative Breast Cancer -Patient is not within five years of diagnosis Germline mutation Carriers: -Patient only carries a HBOC mutation that is classified as "polymorphism" of "favor polymorphism"

Interested in This Trial?

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Conditions

Breast CancerHereditary Breast and Ovarian Cancer

Locations

Hays Medical Center Dreiling-Schmidt Cancer Institute

Hays, Kansas 67601

United States

KCCC West

Kansas City, Kansas 66112

United States

KCCC Overland Park

Overland Park, Kansas 66210

United States

Overland Park Regional Medical Center

Overland Park, Kansas 66215

United States

Salina Regional Health Center - Tammy Walker Cancer Center

Salina, Kansas 67401

United States

The University of Kansas Cancer Center

Westwood, Kansas 66205

United States

Universtiy Health

Kansas City, Missouri 64108

United States

KCCC South

Kansas City, Missouri 64131

United States

Research Medical Center

Kansas City, Missouri 64132

United States

KCCC - North

Kansas City, Missouri 64154

United States

KCCC Lee's Summit

Lee's Summit, Missouri 64064

United States