NCT02306200RecruitingAccepts Healthy Volunteers

Cardiovascular Health Improvement Project

University of Michigan

Start Date

8/1/2013

Completion Date

8/1/2053

Summary

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

Detailed Description

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls. The aims of the study are to collect biological specimens (blood, plasma, serum, aortic tissue) and family history; establish a biobank, establish a comprehensive database with information from consented patients, and provide researchers with high quality well annotated DNA samples with demographic and clinical information.

Eligibility Criteria

Age Range: No minimum to No maximum

Inclusion Criteria: * Any patient over the age of 18 who is able/willing to give informed consent * Patients \<18 years of age with parental consent and assent (if assent is applicable for their age) * Diagnosis of: * aortic pathology potentially due to a known or suspected inherited condition * Idiopathic aortic aneurysm * Interesting of novel vascular pathology in the aorta or main branches * Family history of aortic or vascular disease * Other cardiovascular disease * Healthy controls with no apparent cardiovascular disease Exclusion Criteria: \- Not willing or able to sign the consent

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Conditions

Aortic AneurysmAortic DissectionBicuspid Aortic Valve (BAV)Heart FailureCardiovascular Diseases

Locations

University of Michigan

Ann Arbor, Michigan 48109

United States