NCT02455193NARecruiting

Neuronal Effects of Exercise in Schizophrenia

University of Colorado, Denver

Start Date

8/1/2014

Completion Date

9/1/2025

Summary

This study plans to learn more about how common drugs prescribed to individuals with schizophrenia contribute to weight gain, as well as how exercise and diet impact appetite and the brain's response to food. In this study, the investigators will be evaluating how participants' brains respond to food images as well as asking questions about their food preferences and intake and clinical symptoms. The investigators may also ask participants to complete an exercise or diet intervention to see how this changes brain responses or food preferences.

Eligibility Criteria

Age Range: 21 years to 70 years

Inclusion Criteria: * Diagnosis of schizophrenia or schizoaffective disorder * Between 21 and 70 years of age * Currently prescribed either olanzapine, risperidone, clozapine, or haloperidol, OR not currently being treated with any neuroleptic medications * Weight stable within 5 percent for the last 6 months Exclusion Criteria: * Pregnancy * Substance abuse * Significant endocrine/metabolic disease (e.g., uncontrolled hypertension, severe hypertriglyceridemia) * MRI-specific exclusion criteria (e.g., claustrophobia, metal in the body)

Interventions

BEHAVIORAL

Exercise

BEHAVIORAL

Diet

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Conditions

Schizophrenia

Locations

University of Colorado Anschutz Medical Campus

Aurora, Colorado 80045

United States