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NCT02573753NARecruitingAccepts Healthy Volunteers

The Effects of Sleep on Human Microbiota: Implications for Health and Disease

Mayo Clinic

Start Date

10/1/2015

Completion Date

12/1/2031

Summary

The aggregate of microorganisms inhabiting the human body can be regarded as a dynamic reflector of both healthy and disease states, altering in response to changes in the environment. This may precede clinically detectable disease; and thereby, could be used to predict disease onset and additionally monitor response to treatment and predict prognosis. The primary hypothesis of this pilot study is that the human microbial communities are influenced by sleep and altered in humans with abnormal sleep patterns, and they may ultimately relate to disease risk.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Only subjects who are eligible for ongoing IRB-approved studies will be deemed eligible for this protocol. Exclusion Criteria: * Pregnant or breast-feeding women * Subjects who are ineligible for ongoing IRB-approved studies will not be included in this protocol

Interventions

BEHAVIORAL

Sleep restriction

DIETARY_SUPPLEMENT

Weight gain

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Conditions

Sleep

Locations

Mayo Clinic Rochester

Rochester, Minnesota 55905

United States