Study of Food Aversion in Patients With Anorexia Nervosa
Start Date
11/10/2016
Completion Date
12/31/2027
Summary
This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls. This study determines how heritable and biochemical factors influence food metabolism in anorexia nervosa in order to develop more effective treatment strategies.
Detailed Description
Anorexia nervosa is a brain-based disorder that often leads to serious health consequences including death. The EPHX2 gene has been identified as a susceptibility gene for anorexia nervosa. This study utilizes a multi-omics biomarker system approach to investigate how genetic factors interact with dietary factors to influence food aversion, psychopathology, and clinical outcome in patients with anorexia nervosa.
Eligibility Criteria
Age Range: 18 years to 55 years
Interventions
A breakfast sandwich
Conditions
Locations
UC San Diego Altman Clinical and Translational Research Institute
La Jolla, California 92037
United States
Program for Eating Disorders, Toronto General Hospital
Toronto, Ontario
Canada