NCT03125655RecruitingAccepts Healthy Volunteers
Regulation of Inflammatory Genes in Psoriasis
University of Alabama at Birmingham
Start Date
4/22/2014
Completion Date
4/28/2028
Summary
Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.
Eligibility Criteria
Age Range: 19 years to 99 years
Inclusion Criteria:
* Clinical diagnosis of psoriasis
* Must be age 19 or older.
* Must be Fitzpatrick skin type I, II, III, IV, V, VI.
Exclusion Criteria:
* Subjects who do not have photosensitive disease and are not on photosensitizing medications.
* Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
* Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
* Subjects who are pregnant.
Interventions
DIAGNOSTIC_TEST
Inflammatory markers
Conditions
PsoriasisInflammation
Locations
The Kirklin Clinic
Birmingham, Alabama 35294
United States