NCT03546387Recruiting
Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
Memorial Sloan Kettering Cancer Center
Start Date
5/7/2018
Completion Date
5/7/2027
Summary
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.
Eligibility Criteria
Age Range: 6 years to 17 years
Inclusion Criteria:
* Age ≥ 6 and \< 17 years old
Exclusion Criteria:
* Diagnosis of any secondary disease associated with developmental delay
* History of second cancer diagnosis
* Legal Blindness
* Past surgery of any type, with the exception of enucleation for retinoblastoma
* Past exposure to anesthesia for surgical intervention
* More than one anesthesia encounter for surgical intervention before diagnosis at MSK
* Past External Beam Radiation for treatment of retinoblastoma
* Past systemic chemotherapy
* Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish
Interventions
OTHER
Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V)
OTHER
California Verbal Learning Test, Children's Version
OTHER
Beery Developmental Test of Visual Motor Integration, 6th edition
OTHER
Grooved Pegboard Test
OTHER
Behavior Assessment System for Children/Parent Report
Conditions
Pediatric RetinoblastomaRetinoblastoma
Locations
Memorial Sloan Kettering Cancer Center
New York, New York 10065
United States