A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies
Start Date
7/30/2019
Completion Date
3/21/2026
Summary
A study to assess the effect of multiple doses of venetoclax on the pharmacokinetics of ethinyl estradiol and levonorgestrel in female participants with different hematological malignancies. Upon completion of this study, participants receiving clinical benefit in the opinion of the investigator and without any clinically significant evidence of disease progression with no access to venetoclax (not approved for the treated indication) may continue receiving venetoclax at the discretion of the investigator in a separate extension study.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Venetoclax
ethinyl estradiol/levonorgestrel
Conditions
Locations
Duplicate_Henry Ford Health System /ID# 209090
Detroit, Michigan 48202
United States
Dartmouth-Hitchcock Medical Center /ID# 169097
Lebanon, New Hampshire 03756
United States
Gabrail Cancer Center Research /ID# 207039
Canton, Ohio 44718
United States
Peter MacCallum Cancer Centre-East Melbourne /ID# 225247
East Melbourne, Victoria 3002
Australia