NCT03592290RecruitingAccepts Healthy Volunteers
Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia
Yale University
Start Date
11/15/2017
Completion Date
1/1/2027
Summary
To monitor the changes in central and peripheral monitors/waveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.
Detailed Description
The primary aim of this research is to identify the most robust site for monitoring hypovolemia as well as assess changes in peripheral waveforms monitored by the pulse oximeter collected from different sites (finger, ear, forehead, and nose), blood pressure, cerebral oximetry and peripheral venous pressure during gradual hypovolemia induced by lower body negative pressure (LBNP) in healthy volunteers.
Eligibility Criteria
Age Range: 20 years to 45 years
Inclusion Criteria:
\* Healthy volunteers aged 20-45 with
Exclusion Criteria:
* Pregnant women
* Under 20 years of age
* Subjects with coronary artery disease, diabetes, epilepsy and hypertension
Interventions
DIAGNOSTIC_TEST
Lower body negative pressure
Conditions
HypovolemiaHemodynamic Instability
Locations
John B. Pierce Laboratory
New Haven, Connecticut 06520
United States