NCT03684109NARecruiting
Non-invasive Glioma Characterization Through Molecular Imaging
University of Miami
Start Date
1/25/2019
Completion Date
1/31/2027
Summary
MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.
Detailed Description
This is a pilot study aiming at developing and optimizing MRI-based sequences to provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Adults (≥18 year old)
* Subjects with suspected or confirmed gliomas and who will have a medically indicated biopsy or resection of his/her brain lesion.
Exclusion Criteria:
* Adults unable to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Pregnant women
* Patients unable to have MRI done
Interventions
DEVICE
3T MRI Scanner
Conditions
GliomaBrain TumorPrimary Brain TumorMalignant GliomaMalignant Primary Brain Tumor
Locations
University of Miami
Miami, Florida 33136
United States