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NCT03722537NARecruitingAccepts Healthy Volunteers

Osteochondral Allograft in the Surgical Treatment of Basal Joint Arthritis

Columbia University

Start Date

11/14/2019

Completion Date

3/1/2027

Summary

This is a study comparing the current standard of care surgical treatment to a newer surgical procedure involving the implantation of osteochondral allograft at the base of the thumb. Patients will be followed at 1, 3, 6 months and 1 year post-operatively.

Detailed Description

Basal joint arthritis of the thumb is a common condition associated with considerable morbidity. Many non-operative and operative treatments have been described, but few multicenter prospective evidence based trials exist comparing standard treatments. This continuing search for consensus and improvement of best clinical practice has been reviewed in a thorough meta-analysis of operative treatments for basal joint arthritis. Operative treatments range from osteotomy, partial or complete trapeziectomy with or without reconstruction of the ligaments, tendon interposition to arthrodesis, however the functional outcome varies. Allograft has been previously described in joint replacement / prosthetic implantation surgery in other areas of the body, however not in the thumb. The purpose of this study is to investigate using osteochondral allograft in the surgical intervention phase of treatment for patients with basal joint arthritis.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * 18 years of age or older * Indicated for operative management of basal joint arthritis Exclusion Criteria: * Pregnant women/fetuses/neonates, prisoners * Previously operated on for treatment of basal joint arthritis

Interventions

PROCEDURE

Osteochondral Allograft

PROCEDURE

Ligament Reconstruction Tendon Interposition

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Conditions

Basal Joint Arthritis

Locations

Columbia University Irving Medical Center

New York, New York 10032

United States