NCT03761121NARecruitingAccepts Healthy Volunteers

Developing Fast Pediatric Imaging

Boston Children's Hospital

Start Date

4/15/2019

Completion Date

3/1/2028

Summary

This research study is evaluating the investigational software for magnetic resonance imaging (MRI) systems and techniques to process magnetic resonance (MR) images

Detailed Description

The purpose of the study is to develop new technologies for MRI systems. The new technologies should improve MRI capabilities in terms of how sensitive, specific, and efficient they are. The overall goal is to get better measurements of the brain tumor tissue(s). In this research study, the investigators want to learn more about investigational software and about techniques to process MR images. The testing of investigational software will allow the investigators to improve the image quality. As part of the testing process, the investigators will collect more MR images of the brain, and improve current image reconstruction methods. This will allow a more precise analysis of MR images and potentially better assessment of the brain tumor tissue volume.

Eligibility Criteria

Age Range: No minimum to No maximum

Inclusion Criteria: * Infants, children and adults who have been diagnosed with Low Grade Glioma * Healthy volunteers - Children from age 0 to adults with no upper age limit or; * Diagnosed with LGG and being treated at DFCI; Exclusion Criteria: * Electrical implants such as cardiac pacemakers or perfusion pumps; * Ferromagnetic implants such as aneurysm clips, surgical clips, prosthesis, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants; * Ferromagnetic objects such as jewelry or metal clips; * Women of childbearing age who are seeking to become pregnant, who are breastfeeding, or who suspect they may be pregnant; * Pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions; * Any greater than normal potential for cardiac arrest

Interventions

OTHER

Wave-CAIPI

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Conditions

Pediatric Low-grade Gliomas

Locations

Massachusetts General Hospital

Boston, Massachusetts 02214

United States

Boston Children Hospital

Boston, Massachusetts 02215

United States

Dana Farber Cancer Institute

Boston, Massachusetts 02215

United States