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NCT03897270NARecruitingAccepts Healthy Volunteers

Photoacoustic Imaging of the Breast in Patients With Breast Cancer and Healthy Subjects

Roswell Park Cancer Institute

Start Date

10/25/2018

Completion Date

8/25/2026

Summary

This trial studies photoacoustic imaging of the breast in patients with breast cancer and healthy subjects. Dense breasts typically reduce the sensitivity of a mammography and also is associated with a higher risk of breast cancer. Photoacoustic tomography combines light and sound to provide more information about breast tissue.

Detailed Description

PRIMARY OBJECTIVES: I. To identify photoacoustic features of breast malignancy and treatment response OUTLINE: Participants undergo photoacoustic imaging of the breast over 30 minutes. At subject's discretion, imaging may repeat for a total of 10 studies, each in a separate day.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Women with clinically suspicious or confirmed breast cancer masses (that have not been surgically removed) and will/have already undergo/undergone breast magnetic resonance imaging (MRI). Exclusion Criteria: * Pregnant women (there are no known risks to these procedures, but any unforeseen risks are as yet undetermined, so pregnant women will be excluded by means of a verbal confirmation at time of screening). * Women who have had breast implants in the previous 6 months. * Women who have had lumpectomy * Adults unable to consent. * Individuals who are not yet adults (infants, children, teenagers). * Pregnant women. * Prisoners. * There is no direct benefit of the study to any subject either non-English or English speaker. To facilitate the consent process, we will exclude non-English speaking subjects.

Interventions

PROCEDURE

Photoacoustic Imaging

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Conditions

Breast CarcinomaHealthy Subject

Locations

Roswell Park Cancer Institute

Buffalo, New York 14263

United States