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NCT03918577NARecruiting

Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders

Stanford University

Start Date

5/10/2022

Completion Date

12/30/2026

Summary

This study investigates whether caloric vestibular stimulation can modulate a measure of insight in obsessive-compulsive spectrum disorders.

Detailed Description

Obsessive-compulsive and related disorders (OCRD), including obsessive compulsive disorder and body dysmorphic disorder, are chronic and disabling conditions characterized by recurrent intrusive thoughts and associated compulsive behaviors that affect millions of individuals in the US each year. Individuals affected by OCRD differ in insight, or the degree to which they understand their intrusive thoughts to reflect illness. Impairments in insight limit individuals' motivation to engage in care and predict worse outcome in those who access treatment. This study seeks to explore whether unilateral stimulation of the vestibular system, which activates cortical areas hypothesized to underlie clinical insight, may beneficially modulate insight in individuals with OCRD.

Eligibility Criteria

Age Range: 18 years to 65 years

Inclusion Criteria: * Age 18-65 * Primary diagnosis of Obsessive-Compulsive Disorder, Body Dysmorphic Disorder, Illness Anxiety Disorder or Somatic Symptom Disorder (excluding "with predominant pain") * Strongly held OCRD-related concerns meeting BABS score criterion. * No recent change in psychopharmacological treatment, if any * Capacity to provide informed consent Exclusion Criteria: * Psychiatric or medical conditions (eg, vertigo, history of otological surgery) that might make participation unsafe * Pregnant or nursing women * Active or recent substance use

Interventions

OTHER

Caloric Vestibular Stimulation

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Conditions

Obsessive-Compulsive DisorderBody Dysmorphic DisordersIllness Anxiety Disorder

Locations

Stanford University

Stanford, California 94304

United States