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NCT03999983Recruiting

Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)

St. Louis University

Start Date

11/19/2019

Completion Date

12/1/2026

Summary

A retrospective and prospective registry of patients admitted for stroke and evidence of Vertebral Artery Origin Stenosis (VAOS).

Detailed Description

A retrospective registry of stenting plus medical management for the prevention of recurrent stroke in patients with symptomatic Vertebral Artery origin Stenosis (VAOS). This study is collecting information on clinical outcomes up to 18 months post-treatment. On January 6, 2025, VOTER was changed from prospective to retrospective.

Eligibility Criteria

Age Range: 18 years to 90 years

Inclusion Criteria: 1. Patients between 18 and 90 years of age 2. Patient has experienced a posterior circulation ischemic event 3. Patient has angiographically confirmed bilateral vertebral artery origin disease (Hypoplasia, occlusion, or stenosis). 4. Patient has \>50% stenosis on the side being targeted for therapy Exclusion Criteria: 1. Pregnant women 2. Contrast Indication to the use of anti-platelet drugs 3. There is tandem vertebral or basilar artery stenosis 4. The serum creatinin is \>2.5 5. Baseline modified Rankin score is \>3 6. \< 5 years life expectancy

Interventions

OTHER

Observational Prospective Registry

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Conditions

Vertebral Artery Stenosis

Locations

Baptist Medical Center Jacksonville

Jacksonville, Florida 32207

United States

University of Southern Florida

Tampa, Florida 33606

United States

Northwestern Medicine Regional Medical Group

Winfield, Illinois 60190

United States

University of Iowa

Iowa City, Iowa 52242

United States

SSM DePaul Hospital

Bridgeton, Missouri 63044

United States

Saint Louis University

St Louis, Missouri 63110

United States

Cleveland Clinic

Cleveland, Ohio 44195

United States

Mercy Health Neuroscience Institute

Toledo, Ohio 43608

United States

Semmes Murphey Clinic

Memphis, Tennessee 38120

United States

Texas Tech University Health Science Center of El Paso

El Paso, Texas 79905

United States