Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma
Start Date
1/1/2020
Completion Date
12/31/2027
Summary
Intrahepatic cholangiocarcinoma (ICC) is one of the common malignant tumors. Lymph node metastasis is an important factor affecting the poor prognosis of intrahepatic cholangiocarcinoma. The eighth edition of the AJCC guidelines recommends at least 6 lymph nodes to be used for staging. The American Hepatobiliary and Pancreatic Association also recommends the removal of hilar lymph nodes as part of the radical surgery for intrahepatic cholangiocarcinoma. However, some scholars have found that patients with regional lymph nodes have similar survival rates. This contradictory result has prompted more scholars to conduct clinical research to explore the necessity and standardization of lymph node dissection in intrahepatic cholangiocarcinoma.
Detailed Description
Expanding lymph node dissection can theoretically obtain more lymph node dissection. Obtaining enough lymph nodes can improve the accuracy of AJCC staging and accurately determine prognosis. However, it is unclear whether it will improve the prognosis of patients with lymph node dissection. According to literature reports and related studies, expanded lymph node dissection for right liver tumors included stations 12, 8, and 13, and left lymphoma expanded lymph node dissection includedstations 12, 1, 3, 7, and 8. In summary, standardize the extent of lymph node dissection in intrahepatic cholangiocarcinoma, and obtain enough lymph node dissection under the premise of controlling the complication rate, which is helpful for accurate TNM staging, accurate judgment of prognosis and improvement of survival time. Improve prognosis.
Eligibility Criteria
Age Range: 18 years to 80 years
Interventions
Extend LymphAdenectomy
Conditions
Locations
The Johns Hopkins Hospital
Baltimore, Maryland 10017
United States
China-Japan Friendship Hospital
Beijing, Beijing Municipality
China
Chinese PLA General Hospital
Beijing, Beijing Municipality
China
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Guangzhou, Guangdong
China
Hunan Provincial People's Hospital
Changsha, Hunan
China
The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia
China
Renji Hospital Affiliated to Shanghai Jiao Tong University
Shanghai, Shanghai Municipality
China
Xinhua Hospital Affiliated to Shanghai Jiao Tong University
Shanghai, Shanghai Municipality
China
Zhong Shan Hospital Fudan University
Shanghai, Shanghai Municipality
China
The First Affiliated Hospital of Xi 'an Jiaotong University
Xi’an, Shanxi
China
West China Hospital Sichuan University
Chengdu, Sichuan
China
The Second Affiliated Hospital Zhejiang University School of Medicine
Hanzhou, Zhejiang 310009
China
Zhejiang cancer hospital
Hanzhou, Zhejiang
China