NCT04258787Recruiting
OCT in Fuchs' Dystrophy
Oregon Health and Science University
Start Date
6/26/2020
Completion Date
6/1/2028
Summary
This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Damaged or diseased corneal endothelium from Fuchs' or PBK
* Willingness to commit to required study visits
Exclusion Criteria:
* Prior Endothelial Keratoplasty (EK) or any other surgery except uncomplicated cataract surgery
* Presence of a condition that increases the probability for treatment failure (e.g., heavily vascularized cornea, uncontrolled uveitis)
* Other primary endothelial dysfunction conditions (e.g., posterior polymorphous corneal dystrophy and congenital hereditary corneal dystrophy, iridocorneal endothelial syndrome)
* Central sub-epithelial or stromal scarring that could impact post-operative clarity assessment
* Peripheral anterior synechiae in the angle greater than 3 clock hours
* Hypotony
* Uncontrolled glaucoma
* Visually significant optic nerve or macular pathology
Conditions
Fuchs DystrophyPseudophakic Bullous Keratopathy
Locations
Oregon Health & Science University
Portland, Oregon 97239
United States