NCT04286308NARecruiting
Cortical-Basal Ganglia Speech Networks
Massachusetts General Hospital
Start Date
10/1/2020
Completion Date
2/1/2027
Summary
In this research study the researchers want to learn more about brain activity related to speech perception and production.
Detailed Description
Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.
Eligibility Criteria
Age Range: 18 years to 85 years
Inclusion Criteria:
1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia.
2. Subjects able to provide informed consent and comply with task instructions.
3. Subjects 18-85 years old
Exclusion Criteria:
1. Subjects with reported hearing loss.
2. Non-English-speaking subjects
Interventions
OTHER
electrophysiological data collection
Conditions
Parkinson DiseaseEssential TremorDystonia
Locations
Massachusetts General Hospital
Boston, Massachusetts 02114
United States