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NCT04354064RecruitingAccepts Healthy Volunteers

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Washington University School of Medicine

Start Date

5/29/2019

Completion Date

12/31/2026

Summary

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular residual disease (MRD) detection timepoint. Ultimately, the integration of ctDNA into the clinical workflow has the potential to enhance cancer diagnosis, treatment, surveillance, and prognosis, and guide clinical decision-making in this era of personalized precision medicine.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Eligible healthy donors will be at least 18 years of age. Exclusion Criteria: * Healthy donors younger than 18 years of age

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Conditions

Healthy VolunteerProstate CancerHead and Neck CancerEsophageal CancerGenitourinary CancerSarcomaBreast CancerColon CancerGastrointestinal CancerSolid Tumor CancerLung CancerSkin CancerMelanoma

Locations

Washington University School of Medicine

St Louis, Missouri 63110

United States