Cancer Genetic Testing in Ethnic Populations
Start Date
1/13/2020
Completion Date
10/15/2028
Summary
This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this study may provide an opportunity for cancer risk stratification and individualized screening in these ethnic populations.
Detailed Description
PRIMARY OBJECTIVE: I. To determine the prevalence of genetic mutations in cancer patients from various ethnic populations seeking care at Mayo Clinic Arizona and Mayo Clinic Florida cancer clinics. SECONDARY OBJECTIVES: I. Perform a chart review to assess the impact of genetic testing as part of standard of oncology care: Ia. Determine prevalence of pathogenic germline mutation detected by multi-gene panel testing. Ib. Determine differences in germline mutation detection in these patients as compared to traditional guideline (National Comprehensive Cancer Network \[NCCN\]) based approach for genetic evaluation. OUTLINE: Patients undergo collection of blood or saliva sample for genetic testing.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Biospecimen Collection
Genetic Testing
Conditions
Locations
Mayo Clinic in Arizona
Scottsdale, Arizona 85259
United States
Mayo Clinic in Florida
Jacksonville, Florida 32224-9980
United States