Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Start Date
12/27/2021
Completion Date
8/1/2027
Summary
In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.
Eligibility Criteria
Age Range: 45 years to No maximum
Interventions
NSAID capsules
Opioid capsule
Conditions
Locations
Stanford Health Care
Redwood City, California 94063
United States
University of Utah Health Care
Salt Lake City, Utah 84112-
United States