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NCT04843371RecruitingAccepts Healthy Volunteers

PPG to Predict Ejection Fraction and Other Echographic Data in the General Population

Tulane University

Start Date

8/20/2021

Completion Date

12/1/2026

Summary

The investigators are aiming to investigate the association between ejection fraction (EF) determined by echocardiography and signals obtained from Photoplethysmography (PPG) in the general population. The investigators are also aiming to investigate the association between blood pressure and signals obtained from PPG in the general population. Finally, the investigators are also aiming to investigate the association between signals obtained from PPG in the general population to cardioechographic findings such as, valvular heart disease, structural heart diseases, cardiomyopathies, pericardial disease etc.

Detailed Description

The investigators are proposing a cross-sectional cohort study, where any individual, 18 years old or older, scheduled for an echocardiography at Tulane University's outpatient cardiology clinic can be included. After consenting participants, information on their demographics, personal health habits, medications, and medical history will be collected via reviewing, their electronic medical health records. All participants will undergo an echocardiography as part of their routine medical care by their treating physician. Important echocardiographic findings will be noted such as, EF, valvular heart disease, pericardial disease, cardiomyopathies and structural heart disease. Additionally, PPG recordings will be collected simultaneously while performing echography using the Biostrap wristband. The investigators will analyze the association between each echographic imaging feature, and the PPG waveform obtained. PPG waveform features will be used to develop a predictive model capable of calculating an estimate of ventricular ejection fraction without echocardiography. All echocardiograms will be performed by experienced operators at Tulane Medical Center facilities. The study will occur at a single study site Tulane Medical Center and clinics, with appropriate facilities and equipment to conduct the study accurately and safely. An experienced echocardiogram technician or cardiology fellow will collect the PPG recordings using the Biostrap application. De-identified echocardiogram reports, including information on LVEF will be matched with the participant's pulse report.

Eligibility Criteria

Age Range: 18 years to 120 years

Inclusion Criteria: * Male or Female aged18 years or older. * Patients scheduled to undergo an echocardiogram at Tulane Medical Center. Exclusion Criteria: * Participants under 18 years of age. * Participants with cognitive impairments. * Participants with a physical inability to wear the Biostrap during the echocardiogram. * Individuals who cannot read, speak, and/or understand English.

Interventions

DIAGNOSTIC_TEST

Photoplethysmography

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Conditions

Valvular Heart DiseasePericardial DiseaseCardiomyopathies

Locations

East Jefferson General Hospital

New Orleans, Louisiana 70006

United States

University Medical Center

New Orleans, Louisiana 70112

United States

Tulane Doctors - Speciality Care - Napoleon

New Orleans, Louisiana 70115

United States