NCT04874220NARecruitingAccepts Healthy Volunteers

Neural Correlates of Real World Spatial Navigation in Humans

Duke University

Start Date

9/30/2020

Completion Date

6/30/2026

Summary

The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.

Eligibility Criteria

Age Range: 12 years to 70 years

Inclusion Criteria: * 12 years of age or older and has undergone RNS system placement * Willing to provide informed consent and participate the study * Ability to read and write English fluently Exclusion Criteria: * Unwilling to provide informed consent

Interventions

DEVICE

Deep Brain Stimulation

BEHAVIORAL

Memory and spatial navigation tasks

BEHAVIORAL

Physiological Signals

BEHAVIORAL

Questionnaires and Assessments

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Conditions

Memory, Delayed

Locations

University of California, Los Angeles

Los Angeles, California 90024

United States

Duke University

Durham, North Carolina 27705

United States