NCT04906863RecruitingAccepts Healthy Volunteers
Genetic Studies of Early-onset Dementia
Columbia University
Start Date
9/14/2016
Completion Date
4/30/2028
Summary
The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of 70 years) across all ethnic groups, including Alzheimer's Disease, mild cognitive impairment and other dementias.
Detailed Description
The study population includes individuals with Alzheimer's disease, mild cognitive impairment, other forms of dementia, as well as cognitively healthy individuals with a family history of dementia. Participants include males and females across all racial and ethnic groups.
Eligibility Criteria
Age Range: 35 years to No maximum
Inclusion criteria:
* 35 years and older
* Individuals experiencing memory concerns or diagnosed with dementia and their family members that are unrelated healthy controls without dementia.
Exclusion Criteria:
\- Individuals with competing diagnosis such as Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc., unless family members of a dementia affected individual
Interventions
GENETIC
Blood draw
OTHER
Neurocognitive testing
OTHER
Medical questionnaire
Conditions
Dementia, Early OnsetAlzheimer Dementia (AD)Mild Cognitive Impairment (MCI)Memory Loss
Locations
Columbia University Irving Medical Center
New York, New York 10032
United States