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NCT05084352Recruiting

Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

University of Maryland, Baltimore

Start Date

3/29/2021

Completion Date

10/31/2026

Summary

This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.

Eligibility Criteria

Age Range: 18 years to 79 years

Inclusion Criteria: * Arrival to the hospital within 6 hours of injury * Age \>= 18 years old * Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings. Exclusion Criteria: * Deemed to have a non-survivable TBI * Brain dead on arrival * Active substance abuse for opiates and cocaine as noted by admission toxicology screen. * Any thoracic or abdominal injury resulting in open surgical intervention * Pregnancy * Prisoners * Active military * Non - English speaking (due to necessity for consent in aims 2 and 3) * Age \> 89 years

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Conditions

Traumatic Brain Injury

Locations

University of Maryland Medical Center

Baltimore, Maryland 21210

United States