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NCT05106387Recruiting

An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

Regeneron Pharmaceuticals

Start Date

10/19/2023

Completion Date

2/23/2028

Summary

The main purpose of this study is to continue to see how vonsetamig works in the body and to monitor the outcomes after kidney transplant for participants previously treated in the R5459-RT-1944 study (NCT05092347). No study drug will be given during this study.

Eligibility Criteria

Age Range: 18 years to 70 years

Inclusion Criteria: 1. Received at least 1 dose of treatment with vonsetamig in study R5459-RT-1944 \[NCT05092347\]. 2. Received after acceptable crossmatching, a kidney transplant while enrolled in study R5459-RT-1944 3. Willing and able to comply with clinic visits and study-related procedures 4. Provide informed consent signed by study patient or legally acceptable representative Exclusion Criteria: 1.There are no exclusion criteria for this study. Note: Other protocol defined Inclusion/Exclusion criteria may apply

Interventions

DRUG

Noninterventional

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Conditions

Chronic Kidney Disease (CKD)

Locations

Cedars-Sinai Medical Center

Los Angeles, California 90048

United States

University of California Irvine

Orange, California 92868

United States

Connie Frank Transplant Center at UCSF

San Francisco, California 94143

United States

Yale University of Medicine

New Haven, Connecticut 06520

United States

Comprehensive Transplant Center

Chicago, Illinois 60611

United States

John Hopkins Hospital

Baltimore, Maryland 21224

United States

University of Minnesota

Minneapolis, Minnesota 55455

United States

New York University Langone Health

New York, New York 10016

United States

Penn Transplant Institute

Philadelphia, Pennsylvania 19104

United States