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NCT05112614Recruiting

Role of Gut Microbiome in Cancer Therapy

Mayo Clinic

Start Date

9/11/2019

Completion Date

10/1/2030

Summary

This study examines how gut microbiome can affect cancer therapy in cancer patients undergoing cancer therapy or stem cell transplant. The human microbiome affects the way some cancer drugs are metabolized in the human body. Information from this study may help doctors improve the way cancer treatment is delivered, and increase its effectiveness and success.

Detailed Description

PRIMARY OBJECTIVE: I. To correlate gut microbiome with specific cancer diagnoses and the clinical response (efficacy), and adverse effects of cancer therapy (single or multiple) and stem cell transplant. OUTLINE: Patients undergo collection of blood and stool samples and have their medical records reviewed.

Eligibility Criteria

Age Range: 18 years to 99 years

Inclusion Criteria: * Age 18-99 * Diagnosis of cancer and undergoing cancer therapy or scheduled to start cancer therapy or undergoing stem cell transplant for any hematological condition Exclusion Criteria: * Unable to provide informed consent * Vulnerable adults

Interventions

PROCEDURE

Biospecimen Collection

OTHER

Electronic Health Record Review

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Conditions

Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm

Locations

Mayo Clinic in Arizona

Scottsdale, Arizona 85259

United States

Mayo Clinic in Florida

Jacksonville, Florida 32224

United States

Mayo Clinic in Rochester

Rochester, Minnesota 55905

United States