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NCT05142800Recruiting

Screening For BCRL In Targeted Therapy For Breast Cancer

Massachusetts General Hospital

Start Date

12/13/2018

Completion Date

9/30/2026

Summary

This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer. A Perometer and Sozo devise will be used to measure volume changes

Detailed Description

This study will compare patients' relative arm volume changes and symptoms data from before drug therapy throughout drug treatment and for up to six months after treatment has finished. A Perometer and Sozo device will be used to measure volume changes All participants will be accrued at Massachusetts General Hospital for a target accrual of 166 participants.

Eligibility Criteria

Age Range: 18 years to 80 years

Inclusion Criteria: * Subjects who are receiving treatment in the MGH Breast Cancer Center who are enrolled in a DF/HCC-regulated targeted therapy trial for the treatment of early or metastatic breast cancer or patients being treated with a targeted therapy that may alter their risk of developing edema or BCRL will be eligible. * Subjects that will be eligible for the study include: * Females between 18 and 80 years of age * With a history of breast cancer * 4 weeks or more post-surgery * With or without edema * Undergoing treatment with targeted therapy for early or metastatic disease. Exclusion Criteria: \- Patients who cannot attain 90 degrees of shoulder abduction (position of measurement with Perometer).

Interventions

DEVICE

Perometer

DEVICE

SOZO device

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Conditions

LymphedemaLymphedema ArmLymphedema of Upper ArmLymphedema of Upper LimbLymphedema of the HandsEdemaEdema ArmBreast Cancer LymphedemaBreast Cancer MetastaticBreast Cancer StageBreast Cancer

Locations

Massachusetts General Hospital

Boston, Massachusetts 02115

United States