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NCT05193305Recruiting

Study of Healthy Cohort for Early Detection of Cancer

Johns Hopkins University

Start Date

2/1/2023

Completion Date

2/28/2043

Summary

Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.

Detailed Description

To conduct a longitudinal cohort study of patients who do not have a malignancy at the time of enrollment and are followed over a 20 year period to see if patients develop a malignancy and associate clinical and lifestyle factors as well as collection of blood. All adults 18 years of age and older undergoing upper or lower endoscopy for routine medical care will be eligible for this study.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * All adults 18 years of age of older undergoing upper or lower endoscopy for routine medical care. Exclusion Criteria: * Persons with current malignancy * Persons with history of malignancy and treatment within last 5 years of enrollment, excluding non-melanoma skin cancer or cervical in-situ. * Persons who are unable or unwilling to provide repeat blood samples and complete follow-up questionnaires * Persons who lack the capacity to provide consent * Persons who do not speak English * Persons who are visually or hearing impaired.

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Conditions

Healthy

Locations

Johns Hopkins Hospital

Baltimore, Maryland 21205

United States