Physio-Anatomy Clinical Data Collection Study

Inclusion Criteria: * Patients \>18 years of age. * Patients provide written informed consent. * Clinical presentation consistent with suspected coronary disease. * Patients who are candidates for PCI and scheduled for coronary diagnostics in the cardiac catheter lab with the intent to perform a physiological assessment for de novo lesions with stenosis, if clinically indicated. Exclusion Criteria: * Presence of acute ST Elevation Myocardial Infarction (STEMI) at the time of the cath lab procedure. * Contraindication for FFR examination or administration of vasodilators. * Bacteremia or sepsis. * Major coagulation system abnormalities. * Severe hemodynamic instability or shock. * Heart Failure NYHA Class IV. * Severe valvular heart disease. * Prior heart transplant. * Acute renal failure based on diagnostic practice of the treating physician at time of screening. * Patient is pregnant. * Patient is currently enrolled in another clinical study that may impact the results of this study. * Patient has other co-morbid condition(s) that, in the opinion of the Investigator, could limit their