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NCT05320835NARecruitingAccepts Healthy Volunteers

A Setting Focus Overdose Prevention Intervention

Johns Hopkins Bloomberg School of Public Health

Start Date

4/30/2022

Completion Date

5/30/2027

Summary

A pilot injection-setting targeted peer-driven intervention to reduce HIV and hepatitis C virus transmission and overdose risk behaviors among people who inject drugs (PWID).

Detailed Description

This is a pilot of an injection setting targeted peer-driven intervention to reduce HIV/HCV transmission and overdose risk behaviors. Participants will be randomized to conditions: 1) Peer education and stocking of semi-public injection settings (SPIS) with risk reduction materials, and the standard of care. Based on their SPIS use, 120 index PWID participants will be selected. A conceptual model for the intervention: The conceptual model is based on social influence, social network, and social cognitive theory. The prior work delineated social influence mechanisms. It is expected that training and modeling of effective communication skills will increase the occurrence of conversations on HIV/HCV and overdose prevention. These conversations will then alter perceived descriptive and prescriptive social norms of risk behaviors. The prior work is being enhanced by increasing the availability of risk reduction materials as well as the cuing and modeling risk reduction behaviors in risk settings. It has been found that PWID are motivated to conduct peer education; it enhances their status and provides them a prosocial role in the community. It is hypothesized that peer outreach and supply of materials to SPIS will lead to reduced sharing of injection equipment and increased naloxone availability.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Current drug user (opioid use in the prior two weeks) Exclusion Criteria: * Any mental or physical health impairment that impedes ability to participate

Interventions

BEHAVIORAL

HIV, HCV and overdose prevention

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Conditions

HIV InfectionsHCVDrug Overdose

Locations

Lighthouse Studies at Peer Point

Baltimore, Maryland 21205

United States