NCT05356286NARecruiting

Recording of Intraoperative Spinal Cord Stimulation and Monitoring

University of California, Los Angeles

Start Date

1/21/2011

Completion Date

1/22/2027

Summary

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized. Exclusion Criteria: * none

Interventions

DEVICE

epidural electrical stimulation

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Conditions

Cervical StenosisDisk, HerniatedSpondylosis

Locations

University of California, Los Angeles

Los Angeles, California 90095

United States