A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Diet in Cancer Patients Receiving Chemotherapy
Start Date
4/15/2022
Completion Date
6/1/2027
Summary
Caloric restriction may alter the response to chemotherapy induced stress response and enhance its antitumor effect. This study intends to use an intermitted caloric restriction protocol with alternate days before the chemotherapy administration to enhance the cytotoxic effect generated by standard treatment of cancer.
Detailed Description
This pilot trial will provide preliminary evidence that 1) intermittent caloric restriction and a plant-based diet is feasible in cancer patients; 2) intermittent caloric restriction and a plant-based diet can be safely combined with standard chemotherapy; and 3) intermittent caloric restriction and a plant-based diet may reduce the side effects but increase the antitumor effects of standard chemotherapy.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Diet
Conditions
Locations
University at Buffalo / Great Lakes Cancer Care
Buffalo, New York 14203
United States
University at Buffalo / Great Lakes Cancer Care
Buffalo, New York 14206
United States