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NCT05424029Recruiting

Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

Memorial Sloan Kettering Cancer Center

Start Date

6/14/2022

Completion Date

6/1/2027

Summary

The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors contains enough vesicles to do testing that may help the researchers learn more about their NSCLC.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * All patients ≥ 18 years of age undergoing consideration of surgical resection, including lobar resections, sublobar resections, and pneumonectomies, for primary lung cancer will be eligible. * Patients with previously resected disease and/or previous radiation therapy will be considered on a case by case basis. Exclusion Criteria: * Patients with active infection or pneumonia which may impact exosome makeup * Additionally, if at the discretion of the operating surgeon, obtaining bronchial washings would lead to undue morbidity, the patient would be excluded and replaced

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Conditions

Non-Small Cell Lung Cancer

Locations

Memorial Sloan Kettering Basking Ridge (Consent Only)

Basking Ridge, New Jersey 07920

United States

Memorial Sloan Kettering Monmouth (Consent Only)

Middletown, New Jersey 07748

United States

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey 07645

United States

Memorial Sloan Kettering Suffolk - Commack (Consent Only)

Commack, New York 11725

United States

Memorial Sloan Kettering Westchester (Consent Only)

Harrison, New York 10604

United States

Memorial Sloan Kettering Cancer Center

New York, New York 10065

United States

Memorial Sloan Kettering Nassau (Consent Only)

Uniondale, New York 11553

United States