Inspiratory Muscle Strength Training in Adults With Obesity
Start Date
12/7/2023
Completion Date
7/31/2027
Summary
The purpose of this study is to determine whether inspiratory muscle strength training reduces blood pressure in adults with obesity.
Detailed Description
Obesity affects four-in-ten American adults and is associated with hypertension and greater all-cause mortality. Irrespective of weight loss, aerobic exercise reduces arterial blood pressure (BP) and improves cardiometabolic health. However, nearly half of adults with obesity do not perform aerobic exercise because of low leisure time availability and exertional dyspnea secondary to high chest wall mass-related inspiratory muscle dysfunction. In other clinical populations, emerging data demonstrates time-efficient high-resistance inspiratory muscle strength training (IMST) reduces BP and improves respiratory muscle function. Therefore, the investigators will determine whether eight weeks of daily high-resistance IMST reduces BP, improves respiratory muscle function, and concomitantly reduces exertional dyspnea in a randomized, double-blinded, sham-controlled (i.e., very low-resistance IMST) clinical trial among adults with obesity
Eligibility Criteria
Age Range: 18 years to 45 years
Interventions
High-resistance inspiratory muscle strength training
Very-low-resistance inspiratory muscle strength training
Conditions
Locations
Florida State University
Tallahassee, Florida 32306
United States