Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
Start Date
1/1/2024
Completion Date
12/31/2026
Summary
This initial study is a feasibility study for implementing thoracolumbar interfascial plane, or TLIP, blocks in older adults undergoing spinal fusion. TLIP blocks are done by using anesthesia. In this case, it will be done to either side of the back where surgery will be performed. This has been shown to decrease pain the patients have post-operatively in previous research. In this study, the investigators will examine recruitment rates, completion of assessments, dropout rate, gather patient feedback, and identify barriers to performing TLIP. Further, this feasibility study will provide data to determine adequate sample size and refine methods and outcomes for a future randomized clinical trial. The ultimate goal is to perform a large, appropriately powered randomized control trial to determine the effect of TLIP blocks on pain, physical function and disability, opioid consumption, and delirium in older adult undergoing spinal fusion.
Eligibility Criteria
Age Range: 65 years to No maximum
Interventions
Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine
Blood Test
3D CAM Delirium Severity Scoring
Generalized Anxiety Disorder 7-item (GAD-7) scale
Numerical Rating Score (NRS)
PROMIS-Pain Interference
Oswestry Disability Index (ODI)
Saint Louis University Mental Status Examination (SLUMs)
Delirium Rating Scale-Revised-98 (DRS)
Telephone Interview for Cognitive Status - Modified (TICS-M)
Opioid Equivalents measured by Morphine Milligram Equivalents (MME)
Patient Health Questionnaire depression scale (PHQ-8)
Pain Catastrophizing
Fear Avoidance Beliefs Questionnaire (FABQ)
Opioid Side Effects and Likeability Questionnaire
Daily Pain Trajectory
Tampa Scale of Kinesiophobia
Quality of Recovery 15
Conditions
Locations
University of Iowa
Iowa City, Iowa 52242
United States