NCT05599022NARecruiting
Randomized Assessment of TcMS for VT Storm
University of Pennsylvania
Start Date
5/22/2023
Completion Date
10/1/2028
Summary
Three-arm randomized clinical trial comparing two strategies of TcMS to sham stimulation in patients with VT storm. The hypothesis of the study is that TcMS will reduce the burden of VT in the 24 hours after randomization compared to sham stimulation and that TcMS with theta burst stimulation (TBS) will be more effective at reducing VT burden than low frequency TcMS.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* ≥3 episodes of sustained VT or appropriate ICD therapies within 24 hours despite the use of at least one antiarrhythmic drug
Exclusion Criteria:
* Plan for catheter ablation of VT in the next 24 hours
* Pregnancy
* Contraindication to TcMS (i.e. implantable ventricular assist device, metal implanted in the head or neck \[except the mouth\], implanted medication pumps, cochlear implant, implanted brain stimulator, ocular implant, history of malignancy in the neck)
Interventions
DEVICE
Magnetic Stimulation
Conditions
Ventricular Tachycardia
Locations
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania 19104
United States