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NCT05738096EARLY_PHASE1RecruitingAccepts Healthy Volunteers

Trigeminal Evoked Responses to Improve Rhizotomy

University of Minnesota

Start Date

11/1/2023

Completion Date

11/1/2026

Summary

Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal sensory and nociceptive pathway by using peripheral stimulation of the trigeminal nerve (on the skin) and measuring low latency evoked potentials on the scalp (contralateral sensory cortex). While TSEPs have been measured in the past, it is not clear if implementing TSEPs into a routine neurosurgical rhizotomy procedure will be feasible. This is a prospective cohort study examining the feasibility of routinely performing TSEPs during rhizotomies for TGN.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Adults of 18 years or older * Scheduled to undergo percutaneous rhizotomy for facial pain Exclusion Criteria: * For TGN: Facial pain of unclear origin (i.e. not clearly TGN pain) or Rhizotomy procedure canceled * For Healthy control: Diagnosis or history of facial pain such as TMD or TGN, History of migraine, History of any functional pain disorder: fibromyalgia, IBS, CRPS or Recent chronic pain (within last month)

Interventions

OTHER

TSEP + rhizotomy surgery

OTHER

TSEPs recording only

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Conditions

Trigeminal NeuralgiaRhizotomy

Locations

University of Minnesota

Minneapolis, Minnesota 55455

United States