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NCT05758701PHASE4RecruitingAccepts Healthy Volunteers

CT TAVR Abdomen Study

University of Maryland, Baltimore

Start Date

9/19/2023

Completion Date

3/1/2028

Summary

A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.

Eligibility Criteria

Age Range: 18 years to 88 years

Inclusion Criteria: * scheduled to receive TAVR abdominal CT Exclusion Criteria: * cannot undergo CT scan * Allergy to intravenous contrast not controlled by steroids or benadryl * GFR\<30

Interventions

COMBINATION_PRODUCT

Iodinated Contrast Agent (Omnipaque)

DEVICE

Dual Energy CT

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Conditions

Transcatheter Aortic Valve Replacement

Locations

University of Maryland Medical Center

Baltimore, Maryland 21201

United States