Back to Trials
NCT05795179NARecruitingAccepts Healthy Volunteers

Stress & Self-Control Costs

NYU Langone Health

Start Date

10/1/2024

Completion Date

4/1/2028

Summary

Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms underlying these costs are unknown. To address this, the investigators will use a validated decision-making task that measures how much individuals will pay (from a study endowment) to restrict access to tempting rewards that may lead to self-control failures. The investigators will examine these costs to identify their cognitive, neural and affective mechanisms. First, the investigators will identify the cognitive and computational mechanism that gives rise to self-control costs. Second, the investigators will characterize the neural correlates of self-control costs and identify neural mediators and connectivity patterns stemming from these costs. Finally, the investigators will examine how different classes of stressors (physical, social, or lifetime stress) shape the behavioral and neural representations of self-control costs.

Eligibility Criteria

Age Range: 18 years to 70 years

Inclusion Criteria: * 18-70 years of age, able to speak, read, and write fluently in English * be willing and able to follow study procedures and provide informed consent. * Must additionally confirm they are on a diet to maintain/lose weight and are implementing/maintaining dietary changes. Exclusion Criteria: * History of or medication for neurologic or psychiatric disease * High-blood pressure or heart condition * Diabetes, food allergies, metabolic disorders or history of eating disorder * Use of corticosteroids or beta-blockers * Metallic implants or devices contraindicating magnetic resonance imaging. * Pregnancy is considered an exclusion criteria due to all stress and scanning procedures, thus pregnant participants will not be permitted to participate in the study.

Interventions

BEHAVIORAL

Cold-Pressor Task (CPT)

BEHAVIORAL

Trier Social Stress Test (TSST)

BEHAVIORAL

Modified Non-Stress CPT

BEHAVIORAL

Modified Non-Stress TSST

DEVICE

Functional Magnetic Resonance Imaging (fMRI)

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Self-Control

Locations

NYU Langone Health

New York, New York 10016

United States