NCT05815199NARecruiting
E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness
NYU Langone Health
Start Date
11/13/2023
Completion Date
3/1/2026
Summary
In this open-label, randomized controlled trial study, participants who smoke combustible cigarettes (CC) and are diagnosed with Serious Mental Illness (SMI) will be randomized in two arms to receive harm-reduction counseling and Ecological Momentary Intervention text messaging (EMI) along with either e-cigarettes (EC) or nicotine replacement therapy (NRT) such as patch and lozenges to compare the efficacy in CC smoking reduction.
Eligibility Criteria
Age Range: 21 years to No maximum
Inclusion Criteria:
* Currently smokes 5 or more CPD
* Willingness and ability to provide informed consent
* Age of at least 21 years
* Has SMI diagnosis (such as Schizophrenia, Schizoaffective disorders, Bipolar disorder, Depressive disorders, Trauma and stressor related disorders etc.) as determined using the MINI tool
* Interested in reducing CC smoking but not necessarily trying to quit
* Own a mobile phone or have regular access to a mobile phone
* Able to provide an additional contact to improve follow-up rates
Exclusion Criteria:
* Is pregnant or breastfeeding
* Used tobacco other than CC in the past 2 weeks (e.g., EC, cigarillo)
* Currently engaged in an attempt to quit CC
* Change in dose of their psychotropic medication(s) in the last 30 days
* Meeting DSM-V criteria for current alcohol or substance use disorder except for nicotine use disorder and active mild alcohol or substance use disorders.
* Past month suicidal ideation/suicide attempt and/or psychiatric hospitalization in the last 30 days
Interventions
OTHER
E-cigarette (EC)
OTHER
Nicotine Replacement Therapy (NRT)
BEHAVIORAL
Harm-Reduction Counseling
BEHAVIORAL
Ecological Momentary Intervention (EMI) Text Messaging
Conditions
Cigarette Smoking
Locations
NYU Langone Health
New York, New York 10016
United States