A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer
Start Date
4/26/2023
Completion Date
5/23/2028
Summary
The purpose of this study is to identify the recommended phase 2 regimen(s) RP2R(s) of pasritamig and combination regimens in Part 1 (dose escalation) and to determine safety at the putative RP2R(s) of pasritamig with the combination regimens in Part 2 (dose expansion).
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Pasritamig
Cetrelimab
Cabazitaxel
Docetaxel
Apalutamide
Enzalutamide
Darolutamide
Abiraterone acetate plus prednisone (AAP)
Lutetium Lu-177 vipivotide tetraxetan
JNJ-101556143
Conditions
Locations
Florida Cancer Specialists
Sarasota, Florida 34232
United States
Start Midwest
Grand Rapids, Michigan 49546
United States
Washington University School Of Medicine
St Louis, Missouri 63110
United States
Perlmutter Cancer Center at NYU Langone Brooklyn
Brooklyn, New York 11223
United States
Laura & Isaac Perlmutter Cancer Center at NYU Langone Hospital - Long Island
Mineola, New York 11501
United States
NYU Langone Health
New York, New York 10016
United States
Sidney Kimmel Cancer Center - Jefferson Health
Philadelphia, Pennsylvania 19107
United States
Icon Cancer Centre Kurralta Park
Kurralta Park, 5037
Australia
Macquarie University
Macquarie University, 2109
Australia
Peter MacCallum Cancer Centre
Melbourne, 3000
Australia
Princess Alexandra Hospital
Woolloongabba, 4102
Australia
Hosp Univ Vall D Hebron
Barcelona, 8035
Spain
Hosp Univ Fund Jimenez Diaz
Madrid, 28040
Spain
Hosp. Univ. 12 de Octubre
Madrid, 28041
Spain
Hosp Univ Hm Sanchinarro
Madrid, 28050
Spain