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NCT05832307NARecruitingAccepts Healthy Volunteers

The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program

University of Colorado, Denver

Start Date

10/31/2024

Completion Date

7/31/2027

Summary

This study plans to learn more about whether a stakeholder-informed, standardized inpatient vaccination program will increase influenza vaccination rates of hospitalized children across US pediatric health systems. The first part of the study is to form a multidisciplinary team of stakeholders, including parents, providers, nurses, pharmacists, informaticists, data analysts and communication experts across three sites in synthesizing a best practice implementation guide for an inpatient influenza vaccination program, which will then be piloted at these three sites.

Detailed Description

The overarching goal of this proposal is to determine whether a stakeholder-informed, standardized inpatient influenza vaccination program will increase influenza vaccination rates of hospitalized children across diverse U.S. pediatric health systems. Building upon preliminary data and experience with pediatric inpatient influenza vaccine delivery, the investigators will engage a multidisciplinary team of stakeholders in synthesizing a best practice implementation guide for an inpatient influenza vaccination program across three sites. The next phase of the study, using a novel adaptive trial design, will be to implement and test the program across 12 health systems. Finally, the investigators will evaluate the program's impact using an established dissemination and implementation framework.

Eligibility Criteria

Age Range: No minimum to 99 years

Inclusion Criteria: * At least 6 months of age * Admitted to an inpatient unit at a participating health system Exclusion: \- Admission to critical care sites or hematology-oncology services Exclusion Criteria: * At least 6 months of age * Admitted to an inpatient unit at a participating health system Exclusion: \- Admission to critical care sites or hematology-oncology services

Interventions

OTHER

Existing Influenza Vaccination Practices

OTHER

Standardized inpatient influenza vaccination program

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Conditions

Influenza

Locations

Ann and Robert Lurie's Children Hospital of Chicago

Chicago, Illinois 60611

United States

Seattle Children's Hospital

Seattle, Washington 98105

United States