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NCT05854303Recruiting

Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

Mayo Clinic

Start Date

9/18/2023

Completion Date

11/1/2026

Summary

The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: \- Patients enrolled in the Pain Rehabilitation Center for opioid cessation, with or without esophageal symptoms. Exclusion Criteria: * Inability to provide informed consent. * Patients with previous gastroesophageal surgery or pneumatic dilation. * Esophageal botulinum toxin injection within the prior 12 months. * Esophageal stricture * Achalasia types I and II * Allergy to Lidocaine or other local anesthetics * Subjects on anticoagulation * Bilateral nasal obstruction * Pregnancy or breast feeding

Interventions

BEHAVIORAL

Opioid cessation

OTHER

No opioid cessation

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Conditions

Opioid-Induced Esophageal Dysfunction

Locations

Mayo Clinic Minnesota

Rochester, Minnesota 55905

United States