NCT05860803NARecruiting
Breathing Training and Exercise Capacity in Non-CFB
Mayo Clinic
Start Date
1/15/2024
Completion Date
12/1/2026
Summary
The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to exercise, the function of the lungs and breathing muscles, and general clinical status in people with non-cystic fibrosis bronchiectasis (non-CFB).
Eligibility Criteria
Age Range: 21 years to 80 years
Inclusion Criteria:
* Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks.
* Able and willing to provide informed consent to participate in the study.
Exclusion Criteria:
* Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise.
* Presence of advanced heart failure.
* Current use of antibiotics.
* Acute exacerbation(s) within 3-weeks prior to study commencement.
* Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.
Interventions
DEVICE
LungTrainers
BEHAVIORAL
LungTrainers Pulmonary Rehabilitation regime
Conditions
Non-cystic Fibrosis Bronchiectasis
Locations
Mayo Clinic Florida
Jacksonville, Florida 32224
United States