NCT05864521NARecruitingAccepts Healthy Volunteers

Beetroot Juice and Sleep

Mayo Clinic

Start Date

9/28/2023

Completion Date

6/1/2026

Summary

The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.

Eligibility Criteria

Age Range: 18 years to 80 years

Inclusion Criteria: * 18-35 or 65-80 years of age Exclusion Criteria: * Coronary artery disease * Heart failure * Pregnancy * Diabetes * Sleep disorders * Shift workers * Individuals who typically go to sleep after midnight * Individuals who traveled across ≥2 time zones within one week of study visits * Individuals with a history frequent kidney stones * BMI ≥35.0kg/m2 * Use of nicotine-containing products within the two years preceding study visits * Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with the nitrate-nitrite-nitric oxide pathway or outcome measures

Interventions

DIETARY_SUPPLEMENT

Active Beetroot Juice Supplement (aBRJ)

DIETARY_SUPPLEMENT

Placebo Beetroot Juice Supplement (pBRJ)

Interested in This Trial?

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Conditions

Healthy

Locations

Mayo Clinic in Rochester

Rochester, Minnesota 55905

United States